Lawrence J Hirsch Selected Research

miglustat (Zavesca)

10/2021

Miglustat Therapy for SCARB2-Associated Action Myoclonus-Renal Failure Syndrome.

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Lawrence J Hirsch Research Topics

Disease

33	Seizures (Absence Seizure) 01/2023 - 02/2002
27	Epilepsy (Aura) 03/2024 - 07/2003
25	Status Epilepticus (Complex Partial Status Epilepticus) 03/2024 - 02/2002
7	Critical Illness (Critically Ill) 01/2022 - 09/2009
6	Partial Epilepsies (Epilepsy, Partial) 01/2022 - 12/2002
5	Drug Resistant Epilepsy 11/2017 - 07/2006
4	Encephalitis (Encephalitis, Rasmussen) 01/2023 - 09/2012
2	Infections 03/2024 - 09/2006
2	Inflammation (Inflammations) 01/2023 - 01/2023
2	Coma (Comas) 02/2021 - 09/2017
2	Cognitive Dysfunction 01/2021 - 01/2018
2	Generalized Epilepsy 10/2020 - 01/2017
2	Limbic Encephalitis (Paraneoplastic Limbic Encephalitis) 01/2018 - 01/2014
2	Hypotension (Low Blood Pressure) 03/2016 - 07/2015
2	Brain Injuries (Brain Injury) 04/2010 - 09/2009
2	Neuralgia (Stump Neuralgia) 11/2006 - 01/2006
2	Migraine Disorders (Migraine) 11/2006 - 01/2006
1	Temporal Lobe Epilepsy 01/2023
1	Vitamin B 6 Deficiency (Pyridoxine Deficiency) 01/2023
1	Heart Arrest (Cardiac Arrest) 01/2022
1	Ischemic Stroke 01/2022
1	Progressive Myoclonic Epilepsies (Progressive Myoclonic Epilepsy) 10/2021
1	Gaucher Disease (Gaucher's Disease) 10/2021
1	Ataxia (Dyssynergia) 10/2021
1	Myoclonus (Nocturnal Myoclonus) 10/2021
1	Neurologic Manifestations (Neurological Manifestations) 10/2021
1	Myoclonic Epilepsies (Myoclonic Encephalopathy) 05/2021
1	Disease Progression 01/2019
1	Glioma (Gliomas) 01/2018
1	Sepsis (Septicemia) 09/2017
1	Idiopathic Generalized Epilepsy 01/2017
1	Hippocampal Sclerosis 01/2017

Drug/Important Bio-Agent (IBA)

22	Anticonvulsants (Antiepileptic Drugs)IBA 10/2020 - 02/2002
7	Midazolam (Versed)FDA LinkGeneric 03/2024 - 02/2002
7	Anesthetics (Anesthetic Agents)IBA 01/2023 - 07/2002
6	BenzodiazepinesIBA 03/2024 - 07/2005
5	Lamotrigine (Lamictal)FDA LinkGeneric 01/2013 - 09/2005
4	AntibodiesIBA 01/2018 - 01/2014
4	Levetiracetam (Keppra)FDA LinkGeneric 03/2016 - 12/2002
3	Propofol (Diprivan)FDA LinkGeneric 03/2024 - 02/2002
3	Biomarkers (Surrogate Marker)IBA 01/2023 - 05/2010
3	Phenytoin (Dilantin)FDA LinkGeneric 01/2018 - 09/2005
2	Ketamine FDA LinkGeneric 03/2024 - 08/2013
2	Pentobarbital (Nembutal)FDA Link 03/2024 - 02/2002
2	CytokinesIBA 01/2023 - 01/2023
2	SodiumIBA 01/2018 - 01/2007
2	Lacosamide FDA Link 01/2018 - 03/2016
2	Complement System Proteins (Complement)IBA 01/2018 - 06/2015
1	Intravenous AnestheticsIBA 03/2024
1	Thiopental (Pentothal)FDA Link 03/2024
1	tocilizumab (atlizumab)FDA Link 03/2024
1	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 03/2024
1	Dexamethasone (Maxidex)FDA LinkGeneric 03/2024
1	Pyridoxal Phosphate (Pyridoxal 5 Phosphate)IBA 01/2023
1	ChemokinesIBA 01/2023
1	Diazepam (Valium)FDA LinkGeneric 01/2023
1	Vigabatrin FDA Link 01/2022
1	EnzymesIBA 01/2022
1	gamma-Aminobutyric Acid (GABA)IBA 01/2022
1	Calcium Channels (Calcium Channel)IBA 01/2022
1	Neurotransmitter Agents (Neurotransmitter)IBA 01/2022
1	Prostaglandins BIBA 01/2022
1	Pregabalin (Lyrica)FDA Link 01/2022
1	Glucosylceramides (Glucocerebrosides)IBA 10/2021
1	GlycosphingolipidsIBA 10/2021
1	Scavenger Receptors (Scavenger Receptor)IBA 10/2021
1	miglustat (Zavesca)FDA Link 10/2021
1	Antisense OligonucleotidesIBA 05/2021
1	dimemorfan (AT 17)IBA 01/2020
1	Lorazepam (Ativan)FDA LinkGeneric 01/2019
1	Hypnotics and Sedatives (Sedatives)IBA 12/2018
1	AlbuminsIBA 01/2018
1	Losartan (Cozaar)FDA LinkGeneric 01/2018
1	HMGB1 Protein (HMG1)IBA 01/2018
1	Adenosine (Adenocard)FDA LinkGeneric 01/2018
1	Immunoglobulin G (IgG)IBA 01/2018
1	Isoflurane FDA LinkGeneric 01/2018
1	Leucine (L-Leucine)FDA Link 01/2018
1	anti-leucine-rich glioma-inactivated 1 autoantibodyIBA 01/2018
1	fosphenytoin (Cerebyx)FDA LinkGeneric 01/2018
1	lead selenideIBA 11/2017
1	N 30IBA 09/2017

Therapy/Procedure

20	Therapeutics 01/2023 - 02/2002
8	Critical Care (Surgical Intensive Care) 01/2023 - 07/2003
4	Electrodes (Electrode) 10/2020 - 11/2004
3	Immunotherapy 03/2024 - 01/2014
3	Vagus Nerve Stimulation 12/2021 - 01/2017
2	Drug Therapy (Chemotherapy) 05/2021 - 08/2014
1	Immunomodulation 03/2024
1	Lasers (Laser) 01/2023
1	Anesthesia 01/2023
1	Minimally Invasive Surgical Procedures 01/2023
1	Decompressive Craniectomy 01/2022
1	Neurosurgical Procedures 01/2022
1	Injections 01/2022
1	Deep Brain Stimulation 12/2021
1	Ovariectomy (Oophorectomy) 02/2021
1	Ketogenic Diet 02/2021
1	Length of Stay 12/2018
1	Topical Administration 01/2018